Controlled biosynthesis of actinomycin with sarcosine

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منابع مشابه

Controlled biosynthesis of actinomycin with sarcosine.

Henschler, D. (1956). Hoppe-Seyl. Z. 305, 97. Henschler, D. (1957). Hoppe-Seyl. Z. 309, 276. Hestrin, S. (1949). J. biol. Chem. 180, 249. Hestrin, S. (1950). Biochim. biophys. Acta, 4, 310. Holtz, P. & Schumann, H. G. (1954). Naturwissen8chaften, 41, 306. Kalckar, H. M. (1947). J. biol. Chem. 167, 461. Kaplan, N. 0. & Lipmann, F. (1948). J. biol. Chem. 174,37. Kennedy, E. P. (1956). Canad. J. B...

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3-Hydroxy-4-methylkynurenine as an intermediate in actinomycin biosynthesis.

tryptophan1.2). The formation of 3-hydroxy-4-methylanthranilic acid probably involves a diversion of the well-known metabolic pathway leading to the formation of 3-hydroxyanthranilic acid from L-tryptophan2). However, the mechanismof transmethylation of the aromatic ring has not been examined to the extent of determining which of the alternative compounds mentioned in Fig. 1 is the pentultimate...

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Experimental studies with actinomycin D.

Actinomycin D has been tested on mouse tu mors, with varying degrees of success, as an anti-neoplastic agent. Dramatic inhibition of some ascites (mouse) tumors has been reported by Sugiura (14) and Gregory et al. (6). Reilly (11) and Sugiura (14) are in agreement that actino-mycin D has slight antineoplastic activity against S-180, and Farber (3) demonstrated antitumor activity against the mal...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1959

ISSN: 0306-3283

DOI: 10.1042/bj0730458